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Nancy L Saccone Selected Research

Tobacco Use Disorder (Nicotine Dependence)

11/2021Studying the Utility of Using Genetics to Predict Smoking-Related Outcomes in a Population-Based Study and a Selected Cohort.
1/2018Is the Fagerström test for nicotine dependence invariant across secular trends in smoking? A question for cross-birth cohort analysis of nicotine dependence.
1/2018Leveraging Genomic Data in Smoking Cessation Trials in the Era of Precision Medicine: Why and How.
1/2017Targeted sequencing identifies genetic polymorphisms of flavin-containing monooxygenase genes contributing to susceptibility of nicotine dependence in European American and African American.
3/2016Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts.
10/2015A multiancestry study identifies novel genetic associations with CHRNA5 methylation in human brain and risk of nicotine dependence.
5/2014Multiple distinct CHRNB3-CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans.
1/2014A glimpse into the future - Personalized medicine for smoking cessation.
12/2013Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking.
6/2012Nicotine dependence and comorbid psychiatric disorders: examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes.
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Nancy L Saccone Research Topics

Disease

25Tobacco Use Disorder (Nicotine Dependence)
11/2021 - 01/2007
7Substance-Related Disorders (Drug Abuse)
12/2020 - 12/2003
5Lung Neoplasms (Lung Cancer)
10/2020 - 08/2009
3Alcoholism (Alcohol Abuse)
01/2018 - 01/2008
3Cocaine-Related Disorders (Cocaine Addiction)
03/2016 - 08/2008
2Mental Disorders (Mental Disorder)
12/2020 - 06/2012
2Chronic Obstructive Pulmonary Disease (COPD)
10/2020 - 09/2014
2Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder)
10/2019 - 06/2012
2Marijuana Abuse (Cannabis Abuse)
06/2012 - 01/2008
1Atherosclerosis
11/2021
1Hypertension (High Blood Pressure)
11/2021
1Mitochondrial Diseases (Mitochondrial Disease)
01/2021
1Inborn Urea Cycle Disorders
01/2021
1Borderline Personality Disorder (Personality Disorders, Borderline)
12/2020
1Parkinson Disease (Parkinson's Disease)
10/2019
1Opioid-Related Disorders (Opiate Addiction)
10/2015
1Inborn Genetic Diseases (Disease, Hereditary)
01/2015
1Acquired Immunodeficiency Syndrome (AIDS)
04/2013
1Heroin Dependence (Heroin Abuse)
03/2013
1Conduct Disorder (Conduct Disorders)
06/2012
1Major Depressive Disorder (Major Depressive Disorders)
06/2012
1Panic Disorder (Panic Attack)
06/2012
1Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
06/2012
1Social Phobia
06/2012
1Antisocial Personality Disorder (Antisocial Personality)
06/2012
1Dizziness (Lightheadedness)
03/2010
1Lipoma (Lipomata)
03/2008
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
03/2008
1Rheumatoid Arthritis
03/2008
1Celiac Disease (Celiac Sprue)
03/2008
1Autoimmune Diseases (Autoimmune Disease)
03/2008
1Smallpox (Variola)
07/2007
1Fever (Fevers)
07/2007
1Vaccinia
07/2007

Drug/Important Bio-Agent (IBA)

18Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
10/2020 - 01/2007
10NicotineFDA Link
11/2021 - 12/2003
5Cholinergic Agents (Cholinergics)IBA
08/2010 - 01/2007
4Biological ProductsIBA
10/2015 - 01/2008
3Messenger RNA (mRNA)IBA
10/2015 - 08/2009
2Illicit Drugs (Recreational Drugs)IBA
03/2013 - 01/2008
2Amino AcidsFDA Link
08/2009 - 09/2008
2GABA Receptors (GABA Receptor)IBA
03/2009 - 06/2008
2Cholinergic ReceptorsIBA
09/2008 - 01/2007
1Antihypertensive Agents (Antihypertensives)IBA
11/2021
1Valproic Acid (Depakote)FDA LinkGeneric
01/2021
1EnzymesIBA
10/2020
1Dopamine (Intropin)FDA LinkGeneric
10/2019
1dimethylaniline monooxygenase (N-oxide forming) (flavin-containing monooxygenase)IBA
01/2017
1Lysine AcetyltransferasesIBA
11/2016
1Opioid Analgesics (Opioids)IBA
03/2016
1Heroin (Diamorphine)IBA
10/2015
1mu Opioid Receptors (mu Opioid Receptor)IBA
10/2015
1SmokeIBA
09/2014
1CotinineIBA
12/2013
1Pharmaceutical PreparationsIBA
03/2013
14-aminospiroperidolIBA
06/2012
1gamma-Aminobutyric Acid (GABA)IBA
06/2008
1Interleukin-2 (IL2)IBA
03/2008
1interleukin-21 (interleukin 21)IBA
03/2008
1P-2 (P 2)IBA
03/2008
1InterleukinsIBA
07/2007
1Interleukin-18 (Interleukin 18)IBA
07/2007
1Interleukin-1 (Interleukin 1)IBA
07/2007
1Interleukin-4 (Interleukin 4)IBA
07/2007
1VaccinesIBA
07/2007

Therapy/Procedure

2Precision Medicine
12/2020 - 01/2018
1Genomic Medicine
01/2015